WORLD BRAIN TUMOUR STATISTICS
BACKGROUND: When a person is diagnosed with a brain tumour
they and their family are often curious to know how many other people are
similarly afflicted. To obtain an estimate of the worldwide incidence of brain tumours the International Brain Tumour
Alliance (IBTA) approached the Central Brain Tumor Registry of the United
States (CBTRUS) in late 2006 and sought its help to identify the relevant
statistics. In turn, the CBTRUS involved its academic researchers in a study of
the subject. An international teleconference and two meetings took place in
As a starting point CBTRUS studied the GLOBCAN 2002 database to isolate statistics relating to CNS tumours, it being the most recently available collection of world figures.
The IBTA then asked CBTRUS to undertake forward projections to identify a more contemporary estimate and they estimated a figure of 200,697 for 2005 (see below). This is the basis for the figure of at least 200,000 primary, malignant brain tumours.
The IBTA also asked CBTRUS to estimate the worldwide number of primary non-malignant brain tumours and they have come up with an estimate of 187,884. More detail about that aspect of the study project will be made public by CBTRUS in late 2007.
We were also curious to know the statistics for metastatic brain tumours (i.e. brain tumours that arise from a cancer elsewhere in the body) but CBTRUS and its researchers advised that it was “unlikely that modeling templates are available”.
We hope that the work undertaken by CBTRUS on behalf of the IBTA will constitute a contribution to the overall knowledge about brain tumours and will help inform researchers and the general community.
|
Denis Strangman Chair |
Kathy Oliver Secretary |
21 October 2007
Incidence
Rates and Counts for the World-wide Incidence of Primary Malignant
Brain, Nervous System Cancer, GLOBOCAN 2002.
|
|
Rate* |
Count |
||||
|
|
Overall |
Male |
Female |
Overall |
Male |
Female |
|
World,
Malignant |
na |
3.7 |
2.6 |
189,582 |
108,277 |
81,305 |
|
*Per 100,000 and age-standardized to the World
standard. na: not available to compute
in GLOBOCAN 2002 Note: Incidence may be underestimated in the less
developed countries. The World standard has a different age distribution
and structure than the “Brain,
nervous system” is defined by International Classification of Diseases for
Oncology (ICDO) topography codes C70-C72, which includes the brain, meninges, spinal cord, cranial nerves and other parts of
the nervous system. It does not
include brain lymphomas or tumors of the pituitary gland, craniopharyngeal
duct, and pineal gland. World rates have been estimated as the
population-weighted average of: Eastern Africa, Middle Africa, Northern Africa,
Southern Africa, Western Africa, Caribbean, Central America, South America,
Northern America, Eastern Asia, South-Eastern Asia, South-Central Asia,
Western Asia, Central and Eastern Europe, Northern Europe, Southern Europe,
Western Europe, Australia/New Zealand, Melanesia, Micronesia, Polynesia Reference: J. Ferlay, F. Bray, P. Pisani and D.M. Parkin. GLOBOCAN 2002 Cancer Incidence, Mortality and Prevalence Worldwide IARC CancerBase No. 5, version
2.0 IARCPress, Lyon, 2004. |
||||||
Incidence
Rates for the World-wide and Regional Incidence of Primary Malignant Brain,
Nervous System Cancer, GLOBOCAN 2002
Rates are per 100,000
|
Incidence: ASR (World), All ages |
Brain, nervous system-Male |
Brain, nervous system-Female |
|
World |
3.7 |
2.6 |
|
More developed countries |
5.8 |
4.1 |
|
Less developed countries |
3.0 |
2.1 |
|
|
6.5 |
4.5 |
|
|
1.4 |
1.2 |
|
|
3.0 |
2.1 |
|
Central and South America, |
4.5 |
3.4 |
|
|
6.1 |
4.3 |
|
Australia/New |
6.0 |
3.9 |
World
Number of Cases, Deaths and Prevalence Counts for Primary Malignant
Brain, Nervous System Cancer, GLOBOCAN 2002.
|
Brain,
nervous system-Both
sexes (All ages) |
Cases |
Deaths |
1-year
prev. cases |
3-year
prev. cases |
5-year
prev. cases |
|
World |
189582 |
141723 |
88462 |
199361 |
276564 |
|
More developed countries |
74549 |
56926 |
38078 |
85211 |
116229 |
|
Less developed countries |
114735 |
84578 |
50384 |
114150 |
160335 |
|
|
3087 |
2444 |
1493 |
3343 |
4618 |
|
Middle |
178 |
132 |
29 |
67 |
87 |
|
|
2528 |
2057 |
1183 |
2607 |
3558 |
|
|
582 |
475 |
268 |
592 |
812 |
|
|
1828 |
1447 |
941 |
2143 |
2966 |
|
|
1124 |
911 |
479 |
1050 |
1429 |
|
|
3595 |
2413 |
1616 |
3556 |
4855 |
|
|
14310 |
10836 |
6493 |
14142 |
19151 |
|
|
21126 |
14943 |
12593 |
28231 |
38251 |
|
|
50585 |
33027 |
20883 |
49883 |
73443 |
|
South-Eastern |
6836 |
5381 |
3170 |
7096 |
9773 |
|
South |
27089 |
21899 |
12824 |
28177 |
38276 |
|
|
6584 |
5322 |
3068 |
6785 |
9263 |
|
|
15196 |
14049 |
7365 |
16386 |
22343 |
|
|
7171 |
5510 |
3036 |
6801 |
9318 |
|
|
12063 |
8528 |
5543 |
11921 |
15907 |
|
|
13955 |
10974 |
6812 |
14997 |
20234 |
|
Australia/New |
1661 |
1309 |
636 |
1509 |
2167 |
|
Brain,
nervous system-Male
(All ages) |
Cases |
Deaths |
1-year
prev. cases |
3-year
prev. cases |
5-year
prev. cases |
|
World |
108277 |
80084 |
50736 |
113995 |
157689 |
|
More developed countries |
41361 |
31469 |
21452 |
47614 |
64450 |
|
Less developed countries |
66747 |
48494 |
29284 |
66381 |
93239 |
|
|
1555 |
1242 |
748 |
1668 |
2308 |
|
Middle |
85 |
63 |
17 |
38 |
48 |
|
|
1509 |
1228 |
699 |
1538 |
2099 |
|
|
323 |
261 |
150 |
335 |
460 |
|
|
812 |
634 |
459 |
1062 |
1482 |
|
|
629 |
512 |
270 |
597 |
810 |
|
|
2054 |
1350 |
927 |
2044 |
2794 |
|
|
7863 |
5821 |
3631 |
7930 |
10744 |
|
|
11908 |
8339 |
7228 |
16199 |
21902 |
|
|
29555 |
18721 |
12167 |
29103 |
42864 |
|
South-Eastern |
3933 |
3108 |
1805 |
4015 |
5503 |
|
South |
16798 |
13605 |
7922 |
17391 |
23618 |
|
|
3638 |
2940 |
1654 |
3640 |
4956 |
|
|
8150 |
7535 |
3972 |
8567 |
11393 |
|
|
4002 |
3134 |
1715 |
3776 |
5116 |
|
|
6578 |
4717 |
3001 |
6430 |
8553 |
|
|
7867 |
6067 |
3954 |
8671 |
11616 |
|
Australia/New |
970 |
764 |
391 |
929 |
1335 |
|
Brain,
nervous system-Female
(All ages) |
Cases |
Deaths |
1-year
prev. cases |
3-year
prev. cases |
5-year
prev. cases |
|
World |
81305 |
61639 |
37726 |
85366 |
118875 |